Entry Detail



General Information

Database ID:SKCM06358
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:SLC30A4
Full Name:solute carrier family 30 member 4
Category:mRNA
Synonyms:ZNT4|znT-4
Chromosome:chr15
Strand:-
Coordinate:
Start Site(bp):45479611End Site(bp):45522807
Gene Summary:Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]).[supplied by OMIM, Mar 2008]
External Links:
Ensembl ID:ENSG00000104154
HGNC ID:HGNC:11015
Entrez Gene:7782



Expression Profile of SLC30A4 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
NO
YES
hsa-let-7b-5p
YES
NO
YES
hsa-let-7c-5p
YES
NO
YES
hsa-let-7d-5p
YES
NO
YES
hsa-let-7e-5p
YES
NO
YES
hsa-let-7f-5p
YES
NO
YES
hsa-let-7g-5p
YES
NO
YES
hsa-let-7i-5p
YES
NO
YES
hsa-miR-124-3p
YES
NO
YES
hsa-miR-134-5p
YES
YES
YES
hsa-miR-142-5p
YES
NO
YES
hsa-miR-15a-5p
YES
YES
NO
hsa-miR-15b-5p
YES
YES
NO
hsa-miR-16-5p
YES
YES
NO
hsa-miR-195-5p
YES
YES
NO
hsa-miR-219a-5p
YES
YES
YES
hsa-miR-26b-5p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
YES
hsa-miR-30b-5p
YES
YES
YES
hsa-miR-30c-5p
YES
YES
YES
hsa-miR-30d-5p
YES
YES
YES
hsa-miR-30e-5p
YES
YES
YES
hsa-miR-340-5p
YES
YES
YES
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-424-5p
YES
YES
NO
hsa-miR-494-3p
YES
YES
YES
hsa-miR-497-5p
YES
YES
NO
hsa-miR-506-3p
YES
NO
YES
hsa-miR-98-5p
YES
NO
YES
Display: