ctcRbase

Entry Detail

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General Information

Database ID: SKCM06412 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: AMOT Full Name: angiomotin Category: mRNA Synonyms: - Chromosome: chrX Strand: - Coordinate: Start Site(bp): 112774503 End Site(bp): 112840815 Gene Summary: This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000126016 HGNC ID: HGNC:17810 Entrez Gene: 154796

Expression Profile of AMOT Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-1251-5p YES NO YES hsa-miR-1297 YES YES YES hsa-miR-132-3p YES YES YES hsa-miR-141-3p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-205-5p YES YES YES hsa-miR-211-5p YES YES NO hsa-miR-212-3p YES YES YES hsa-miR-223-3p YES YES NO hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-329-3p YES NO NO hsa-miR-330-3p YES NO YES hsa-miR-362-3p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-490-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-505-3p YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-665 YES NO YES hsa-miR-98-5p YES YES YES Display: