ctcRbase

Entry Detail

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General Information

Database ID: SKCM06421 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SLC12A6 Full Name: solute carrier family 12 member 6 Category: mRNA Synonyms: ACCPN|KCC3|KCC3A|KCC3B Chromosome: chr15 Strand: - Coordinate: Start Site(bp): 34229996 End Site(bp): 34338060 Gene Summary: This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000140199 HGNC ID: HGNC:10914 Entrez Gene: 9990

Expression Profile of SLC12A6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-122-5p YES YES YES hsa-miR-1271-5p YES YES YES hsa-miR-137 YES YES YES hsa-miR-143-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-145-5p YES NO YES hsa-miR-155-5p YES YES NO hsa-miR-18a-5p YES YES YES hsa-miR-18b-5p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-760 YES NO YES hsa-miR-96-5p YES YES YES Display: