| ncRNA Symbol: | WIPI2 | | Full Name: | WD repeat domain, phosphoinositide interacting 2 | | Category: | mRNA | | Synonyms: | ATG18B|Atg21|CGI-50|WIPI-2 | | Chromosome: | chr7 | | Strand: | + | | Coordinate: | | Start Site(bp): | 5190188 | End Site(bp): | 5233826 | | | Gene Summary: | WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008] | | External Links: | |
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