ctcRbase

Entry Detail

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General Information

Database ID: SKCM06433 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DGCR8 Full Name: DGCR8, microprocessor complex subunit Category: mRNA Synonyms: C22orf12|DGCRK6|Gy1|pasha Chromosome: chr22 Strand: + Coordinate: Start Site(bp): 20080232 End Site(bp): 20111877 Gene Summary: This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010] External Links: Ensembl ID: ENSG00000128191 HGNC ID: HGNC:2847 Entrez Gene: 54487

Expression Profile of DGCR8 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-132-3p YES YES YES hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-208a-3p YES NO YES hsa-miR-208b-3p YES NO YES hsa-miR-212-3p YES YES YES hsa-miR-31-5p YES YES YES hsa-miR-421 YES YES NO hsa-miR-499a-5p YES YES YES hsa-miR-505-3p YES YES NO hsa-miR-9-5p YES YES YES Display: