ctcRbase

Entry Detail

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General Information

Database ID: SKCM06457 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: FBXL3 Full Name: F-box and leucine rich repeat protein 3 Category: mRNA Synonyms: FBL3|FBL3A|FBXL3A Chromosome: chr13 Strand: - Coordinate: Start Site(bp): 76992598 End Site(bp): 77027195 Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000005812 HGNC ID: HGNC:13599 Entrez Gene: 26224

Expression Profile of FBXL3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-144-3p YES YES YES hsa-miR-145-5p YES YES YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-153-3p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-18a-5p YES YES YES hsa-miR-18b-5p YES YES YES hsa-miR-193a-5p YES NO YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-211-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-299-5p YES NO YES hsa-miR-300 YES NO YES hsa-miR-338-3p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-342-3p YES YES YES hsa-miR-361-5p YES YES NO hsa-miR-369-3p YES NO YES hsa-miR-371a-5p YES YES YES hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-381-3p YES NO YES hsa-miR-410-3p YES YES NO hsa-miR-411-5p YES NO YES hsa-miR-429 YES YES NO hsa-miR-448 YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-499a-5p YES YES YES hsa-miR-519d-3p YES YES YES hsa-miR-542-3p YES NO YES hsa-miR-543 YES YES YES hsa-miR-582-5p YES NO YES hsa-miR-655-3p YES NO YES hsa-miR-875-5p YES YES NO hsa-miR-93-5p YES YES YES hsa-miR-9-5p YES YES YES Display: