ctcRbase

Entry Detail

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General Information

Database ID: SKCM06463 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CRY1 Full Name: cryptochrome circadian regulator 1 Category: mRNA Synonyms: DSPD|PHLL1 Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 106991364 End Site(bp): 107093829 Gene Summary: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014] External Links: Ensembl ID: ENSG00000008405 HGNC ID: HGNC:2384 Entrez Gene: 1407

Expression Profile of CRY1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-448 YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-758-3p YES YES NO Display: