ctcRbase

Entry Detail

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General Information

Database ID: SKCM06466 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ARHGAP26 Full Name: Rho GTPase activating protein 26 Category: mRNA Synonyms: GRAF|GRAF1|OPHN1L|OPHN1L1 Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 142770384 End Site(bp): 143229011 Gene Summary: Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017] External Links: Ensembl ID: ENSG00000145819 HGNC ID: HGNC:17073 Entrez Gene: 23092

Expression Profile of ARHGAP26 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO NO hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-107 YES NO NO hsa-miR-129-5p YES NO YES hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-17-5p YES YES YES hsa-miR-183-5p YES YES YES hsa-miR-186-5p YES YES YES hsa-miR-195-5p YES NO YES hsa-miR-200b-3p YES NO YES hsa-miR-200c-3p YES NO YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-22-3p YES NO YES hsa-miR-24-3p YES NO YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-409-5p YES NO YES hsa-miR-424-5p YES NO YES hsa-miR-429 YES NO YES hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-497-5p YES NO YES hsa-miR-503-5p YES NO NO hsa-miR-519d-3p YES YES YES hsa-miR-93-5p YES YES YES Display: