ctcRbase

Entry Detail

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General Information

Database ID: SKCM06472 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CTNS Full Name: cystinosin, lysosomal cystine transporter Category: mRNA Synonyms: CTNS-LSB|PQLC4|SLC66A4 Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 3636468 End Site(bp): 3661542 Gene Summary: This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009] External Links: Ensembl ID: ENSG00000040531 HGNC ID: HGNC:2518 Entrez Gene: 1497

Expression Profile of CTNS Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-106a-5p YES YES NO hsa-miR-124-3p YES YES YES hsa-miR-17-5p YES YES NO hsa-miR-186-5p YES NO YES hsa-miR-20a-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-486-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-506-3p YES YES YES hsa-miR-98-5p YES YES YES Display: