ctcRbase

Entry Detail

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General Information

Database ID: SKCM06499 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DOT1L Full Name: DOT1 like histone lysine methyltransferase Category: mRNA Synonyms: DOT1|KMT4 Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 2164149 End Site(bp): 2232578 Gene Summary: The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011] External Links: Ensembl ID: ENSG00000104885 HGNC ID: HGNC:24948 Entrez Gene: 84444

Expression Profile of DOT1L Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-128-3p YES NO YES hsa-miR-133a-3p YES NO YES hsa-miR-133b YES NO YES hsa-miR-153-3p YES YES YES hsa-miR-200b-3p NO YES YES hsa-miR-200c-3p NO YES YES hsa-miR-224-5p NO YES YES hsa-miR-27a-3p YES NO YES hsa-miR-27b-3p YES NO YES hsa-miR-429 NO YES YES hsa-miR-448 YES NO YES Display: