ctcRbase

Entry Detail

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General Information

Database ID: SKCM06506 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RFC1 Full Name: replication factor C subunit 1 Category: mRNA Synonyms: A1|MHCBFB|PO-GA|RECC1|RFC|RFC140 Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 39287456 End Site(bp): 39366375 Gene Summary: This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011] External Links: Ensembl ID: ENSG00000035928 HGNC ID: HGNC:9969 Entrez Gene: 5981

Expression Profile of RFC1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-134-5p YES YES NO hsa-miR-136-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-197-3p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES YES hsa-miR-384 YES YES NO hsa-miR-875-5p YES YES NO hsa-miR-93-5p YES YES NO hsa-miR-98-5p YES YES NO Display: