| ncRNA Symbol: | GCNT2 |
| Full Name: | glucosaminyl (N-acetyl) transferase 2 (I blood group) |
| Category: | mRNA |
| Synonyms: | CCAT|CTRCT13|GCNT2C|GCNT5|IGNT|II|NACGT1|NAGCT1|ULG3|bA360O19.2|bA421M1.1 |
| Chromosome: | chr6 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 10492223 | End Site(bp): | 10629368 | |
| Gene Summary: | This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
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