ctcRbase

Entry Detail

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General Information

Database ID: SKCM06518 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RAPH1 Full Name: Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 Category: mRNA Synonyms: ALS2CR18|ALS2CR9|LPD|PREL-2|PREL2|RMO1|RalGDS/AF-6 Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 203394345 End Site(bp): 203535410 Gene Summary: This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016] External Links: Ensembl ID: ENSG00000173166 HGNC ID: HGNC:14436 Entrez Gene: 65059

Expression Profile of RAPH1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-124-3p YES NO YES hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-137 YES NO YES hsa-miR-140-5p YES YES NO hsa-miR-142-3p YES YES NO hsa-miR-145-5p YES YES YES hsa-miR-155-5p YES YES YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-17-5p YES NO YES hsa-miR-185-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-19a-3p YES NO YES hsa-miR-19b-3p YES NO YES hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-214-3p YES NO NO hsa-miR-217 YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-31-5p YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-362-3p YES NO NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-497-5p YES YES NO hsa-miR-519d-3p YES NO YES hsa-miR-541-3p YES NO NO hsa-miR-543 YES YES NO hsa-miR-654-5p YES NO NO hsa-miR-876-5p YES YES NO hsa-miR-93-5p YES NO YES hsa-miR-9-5p YES YES YES Display: