ctcRbase

Entry Detail

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General Information

Database ID: SKCM06586 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BIRC2 Full Name: baculoviral IAP repeat containing 2 Category: mRNA Synonyms: API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 102347211 End Site(bp): 102378670 Gene Summary: The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] External Links: Ensembl ID: ENSG00000110330 HGNC ID: HGNC:590 Entrez Gene: 329

Expression Profile of BIRC2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-145-5p YES YES YES hsa-miR-197-3p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-421 YES YES NO Display: