Entry Detail



General Information

Database ID:SKCM06598
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:SETDB2
Full Name:SET domain bifurcated 2
Category:mRNA
Synonyms:C13orf4|CLLD8|CLLL8|KMT1F
Chromosome:chr13
Strand:+
Coordinate:
Start Site(bp):49444374End Site(bp):49495003
Gene Summary:This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
External Links:
Ensembl ID:ENSG00000136169
HGNC ID:HGNC:20263
Entrez Gene:83852



Expression Profile of SETDB2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-135a-5p
YES
YES
NO
hsa-miR-135b-5p
YES
YES
NO
hsa-miR-29a-3p
NO
YES
YES
hsa-miR-29b-3p
NO
YES
YES
hsa-miR-29c-3p
NO
YES
YES
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