ctcRbase

Entry Detail

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General Information

Database ID: SKCM06658 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DNM2 Full Name: dynamin 2 Category: mRNA Synonyms: CMT2M|CMTDI1|CMTDIB|DI-CMTB|DYN2|DYNII|LCCS5 Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 10718079 End Site(bp): 10833488 Gene Summary: Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010] External Links: Ensembl ID: ENSG00000079805 HGNC ID: HGNC:2974 Entrez Gene: 1785

Expression Profile of DNM2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-124-3p YES NO YES hsa-miR-130a-3p YES NO YES hsa-miR-130b-3p YES NO YES hsa-miR-17-5p YES NO YES hsa-miR-204-5p YES YES YES hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-211-5p YES YES YES hsa-miR-301a-3p YES NO YES hsa-miR-301b-3p YES NO YES hsa-miR-454-3p YES NO YES hsa-miR-503-5p YES YES NO hsa-miR-519d-3p YES NO YES hsa-miR-93-5p YES NO YES Display: