ctcRbase

Entry Detail

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General Information

Database ID: SKCM06668 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: U2AF2 Full Name: U2 small nuclear RNA auxiliary factor 2 Category: mRNA Synonyms: U2AF65 Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 55654146 End Site(bp): 55674715 Gene Summary: U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000063244 HGNC ID: HGNC:23156 Entrez Gene: 11338

Expression Profile of U2AF2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-145-5p YES YES YES hsa-miR-300 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-423-5p YES NO YES hsa-miR-483-3p YES NO YES hsa-miR-485-5p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-668-3p YES NO YES Display: