| ncRNA Symbol: | VEGFB |
| Full Name: | vascular endothelial growth factor B |
| Category: | mRNA |
| Synonyms: | VEGFL|VRF |
| Chromosome: | chr11 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 64234538 | End Site(bp): | 64238793 |
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| Gene Summary: | This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011] |
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