Entry Detail



General Information

Database ID:SKCM06670
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:SEC24D
Full Name:SEC24 homolog D, COPII coat complex component
Category:mRNA
Synonyms:CLCRP2
Chromosome:chr4
Strand:-
Coordinate:
Start Site(bp):118722823End Site(bp):118838683
Gene Summary:The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
External Links:
Ensembl ID:ENSG00000150961
HGNC ID:HGNC:10706
Entrez Gene:9871



Expression Profile of SEC24D Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-154-5p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-196a-5p
YES
YES
NO
hsa-miR-196b-5p
YES
YES
NO
hsa-miR-204-5p
YES
YES
YES
hsa-miR-211-5p
YES
YES
YES
hsa-miR-29a-3p
YES
YES
NO
hsa-miR-29b-3p
YES
YES
NO
hsa-miR-29c-3p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-375
YES
YES
NO
hsa-miR-379-5p
YES
YES
NO
hsa-miR-382-5p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
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