Entry Detail



General Information

Database ID:SKCM06698
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:MRI1
Full Name:methylthioribose-1-phosphate isomerase 1
Category:mRNA
Synonyms:M1Pi|MRDI|MTNA|Ypr118w
Chromosome:chr19
Strand:+
Coordinate:
Start Site(bp):13764532End Site(bp):13774282
Gene Summary:This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD). [provided by RefSeq, Jul 2016]
External Links:
Ensembl ID:ENSG00000037757
HGNC ID:HGNC:28469
Entrez Gene:84245



Expression Profile of MRI1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
YES
NO
hsa-miR-107
YES
YES
NO
hsa-miR-124-3p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-506-3p
YES
YES
NO
hsa-miR-9-5p
YES
YES
NO
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