ctcRbase

Entry Detail

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General Information

Database ID: SKCM06700 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: HDAC4 Full Name: histone deacetylase 4 Category: mRNA Synonyms: AHO3|BDMR|HA6116|HD4|HDAC-4|HDAC-A|HDACA Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 239048168 End Site(bp): 239401654 Gene Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000068024 HGNC ID: HGNC:14063 Entrez Gene: 9759

Expression Profile of HDAC4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-128-3p YES NO YES hsa-miR-1297 YES YES NO hsa-miR-1-3p YES NO YES hsa-miR-140-3p YES NO YES hsa-miR-140-5p YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-17-5p YES NO YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-200b-3p YES NO YES hsa-miR-200c-3p YES NO YES hsa-miR-206 YES NO YES hsa-miR-208a-3p YES NO YES hsa-miR-208b-3p YES NO YES hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-223-3p YES YES YES hsa-miR-22-3p YES NO YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-299-5p YES NO YES hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-302a-3p YES NO YES hsa-miR-302b-3p YES NO YES hsa-miR-302c-3p YES NO YES hsa-miR-302d-3p YES NO YES hsa-miR-302e YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-370-3p YES YES YES hsa-miR-372-3p YES NO YES hsa-miR-373-3p YES NO YES hsa-miR-429 YES NO YES hsa-miR-495-3p YES YES NO hsa-miR-519d-3p YES NO YES hsa-miR-520a-3p YES NO YES hsa-miR-520b YES NO YES hsa-miR-520c-3p YES NO YES hsa-miR-520d-3p YES NO YES hsa-miR-520e YES NO YES hsa-miR-613 YES NO YES hsa-miR-93-5p YES NO YES Display: