ctcRbase

Entry Detail

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General Information

Database ID: SKCM06735 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: OGDH Full Name: oxoglutarate dehydrogenase Category: mRNA Synonyms: AKGDH|E1k|OGDC Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 44606572 End Site(bp): 44709066 Gene Summary: This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009] External Links: Ensembl ID: ENSG00000105953 HGNC ID: HGNC:8124 Entrez Gene: 4967

Expression Profile of OGDH Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-136-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-182-5p YES NO YES hsa-miR-22-3p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-96-5p YES YES YES Display: