ctcRbase

Entry Detail

---



General Information

Database ID: SKCM06741 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: EEF2K Full Name: eukaryotic elongation factor 2 kinase Category: mRNA Synonyms: CaMKIII|HSU93850|eEF-2K Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 22206282 End Site(bp): 22288732 Gene Summary: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000103319 HGNC ID: HGNC:24615 Entrez Gene: 29904

Expression Profile of EEF2K Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-124-3p YES YES YES hsa-miR-142-3p YES YES NO hsa-miR-142-5p YES NO YES hsa-miR-143-3p YES YES NO hsa-miR-196a-5p YES YES YES hsa-miR-196b-5p YES YES YES hsa-miR-22-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-326 YES NO YES hsa-miR-329-3p YES NO NO hsa-miR-330-5p YES NO YES hsa-miR-335-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-370-3p YES YES NO hsa-miR-371a-5p YES NO YES hsa-miR-382-5p YES YES NO hsa-miR-448 YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-874-3p YES NO YES hsa-miR-98-5p YES YES YES Display: