| ncRNA Symbol: | C1GALT1 | | Full Name: | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | | Category: | mRNA | | Synonyms: | C1GALT|T-synthase | | Chromosome: | chr7 | | Strand: | + | | Coordinate: | | Start Site(bp): | 7156934 | End Site(bp): | 7248651 | | | Gene Summary: | The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.[provided by RefSeq, Sep 2010] | | External Links: | |
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