ctcRbase

Entry Detail

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General Information

Database ID: SKCM06796 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TBK1 Full Name: TANK binding kinase 1 Category: mRNA Synonyms: FTDALS4|IIAE8|NAK|T2K Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 64451880 End Site(bp): 64502108 Gene Summary: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010] External Links: Ensembl ID: ENSG00000183735 HGNC ID: HGNC:11584 Entrez Gene: 29110

Expression Profile of TBK1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-155-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-191-5p YES YES NO hsa-miR-192-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-215-5p YES YES NO hsa-miR-21-5p YES YES NO hsa-miR-219a-2-3p YES NO YES hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES YES hsa-miR-497-5p YES YES NO hsa-miR-503-5p YES YES NO hsa-miR-505-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-590-5p YES YES NO Display: