ctcRbase

Entry Detail

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General Information

Database ID: SKCM06804 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PTPRA Full Name: protein tyrosine phosphatase, receptor type A Category: mRNA Synonyms: HEPTP|HLPR|HPTPA|HPTPalpha|LRP|PTPA|PTPRL2|R-PTP-alpha|RPTPA Chromosome: chr20 Strand: + Coordinate: Start Site(bp): 2864184 End Site(bp): 3039076 Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000132670 HGNC ID: HGNC:9664 Entrez Gene: 5786

Expression Profile of PTPRA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-132-3p YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-146a-5p YES YES YES hsa-miR-146b-5p YES YES YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-206 YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-543 YES YES NO hsa-miR-599 YES YES NO hsa-miR-613 YES YES YES hsa-miR-876-5p YES YES NO Display: