ctcRbase

Entry Detail

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General Information

Database ID: SKCM06852 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: VEZT Full Name: vezatin, adherens junctions transmembrane protein Category: mRNA Synonyms: VEZATIN Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 95217746 End Site(bp): 95302790 Gene Summary: This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011] External Links: Ensembl ID: ENSG00000028203 HGNC ID: HGNC:18258 Entrez Gene: 55591

Expression Profile of VEZT Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-101-3p YES YES YES hsa-miR-129-2-3p YES NO YES hsa-miR-129-5p YES YES NO hsa-miR-144-3p YES YES YES hsa-miR-153-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-183-5p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-204-5p YES YES YES hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-211-5p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-31-5p YES YES YES hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-489-3p YES NO YES hsa-miR-490-3p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-708-5p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-9-5p YES YES NO hsa-miR-98-5p YES YES YES Display: