ctcRbase

Entry Detail

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General Information

Database ID: SKCM06865 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: EARS2 Full Name: glutamyl-tRNA synthetase 2, mitochondrial Category: mRNA Synonyms: COXPD12|MSE1|gluRS Chromosome: chr16 Strand: - Coordinate: Start Site(bp): 23522014 End Site(bp): 23557731 Gene Summary: This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015] External Links: Ensembl ID: ENSG00000103356 HGNC ID: HGNC:29419 Entrez Gene: 124454

Expression Profile of EARS2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-136-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-448 YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-455-3p YES NO YES hsa-miR-485-5p YES YES NO hsa-miR-493-3p YES NO YES hsa-miR-505-3p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: