ctcRbase

Entry Detail

---



General Information

Database ID: SKCM06908 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PTPN3 Full Name: protein tyrosine phosphatase, non-receptor type 3 Category: mRNA Synonyms: PTP-H1|PTPH1 Chromosome: chr9 Strand: - Coordinate: Start Site(bp): 109375466 End Site(bp): 109498313 Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009] External Links: Ensembl ID: ENSG00000070159 HGNC ID: HGNC:9655 Entrez Gene: 5774

Expression Profile of PTPN3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-129-2-3p YES NO YES hsa-miR-1297 YES NO YES hsa-miR-1321 YES NO NO hsa-miR-134-5p YES YES NO hsa-miR-145-5p YES NO YES hsa-miR-147a YES NO NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-221-3p YES NO YES hsa-miR-222-3p YES NO YES hsa-miR-26a-5p YES NO YES hsa-miR-26b-5p YES NO YES hsa-miR-28-5p YES YES NO hsa-miR-375 YES NO YES hsa-miR-424-5p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-503-5p YES NO YES hsa-miR-519d-3p YES YES YES hsa-miR-708-5p YES YES NO hsa-miR-93-5p YES YES YES Display: