ctcRbase

Entry Detail

---



General Information

Database ID: SKCM06963 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BAIAP2 Full Name: BAI1 associated protein 2 Category: mRNA Synonyms: BAP2|FLAF3|IRSP53 Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 81035122 End Site(bp): 81117432 Gene Summary: The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009] External Links: Ensembl ID: ENSG00000175866 HGNC ID: HGNC:947 Entrez Gene: 10458

Expression Profile of BAIAP2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-144-3p YES YES NO hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-195-5p YES NO YES hsa-miR-197-3p YES YES NO hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-331-3p YES NO YES hsa-miR-424-5p YES NO YES hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES NO YES Display: