ctcRbase

Entry Detail

---



General Information

Database ID: SKCM07040 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SOS1 Full Name: SOS Ras/Rac guanine nucleotide exchange factor 1 Category: mRNA Synonyms: GF1|GGF1|GINGF|HGF|NS4|SOS-1 Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 38981396 End Site(bp): 39124345 Gene Summary: This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000115904 HGNC ID: HGNC:11187 Entrez Gene: 6654

Expression Profile of SOS1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p NO YES YES hsa-miR-106b-5p NO YES YES hsa-miR-124-3p NO YES YES hsa-miR-132-3p NO YES YES hsa-miR-144-3p NO YES YES hsa-miR-148a-3p NO YES YES hsa-miR-148b-3p NO YES YES hsa-miR-152-3p NO YES YES hsa-miR-17-5p NO YES YES hsa-miR-181a-5p NO YES YES hsa-miR-181b-5p NO YES YES hsa-miR-181c-5p NO YES YES hsa-miR-181d-5p NO YES YES hsa-miR-20a-5p NO YES YES hsa-miR-20b-5p NO YES YES hsa-miR-212-3p NO YES YES hsa-miR-217 NO YES YES hsa-miR-27a-3p NO YES YES hsa-miR-27b-3p NO YES YES hsa-miR-30a-5p NO YES YES hsa-miR-30b-5p NO YES YES hsa-miR-30c-5p NO YES YES hsa-miR-30d-5p NO YES YES hsa-miR-30e-5p NO YES YES hsa-miR-519d-3p NO YES YES hsa-miR-543 NO YES YES hsa-miR-93-5p NO YES YES hsa-miR-9-5p NO YES YES Display: