Entry Detail



General Information

Database ID:SKCM07057
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:GRK4
Full Name:G protein-coupled receptor kinase 4
Category:mRNA
Synonyms:GPRK2L|GPRK4|GRK4a|IT11
Chromosome:chr4
Strand:+
Coordinate:
Start Site(bp):2963608End Site(bp):3040747
Gene Summary:This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
External Links:
Ensembl ID:ENSG00000125388
HGNC ID:HGNC:4543
Entrez Gene:2868



Expression Profile of GRK4 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
Display:N/A