ctcRbase

Entry Detail

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General Information

Database ID: SKCM07142 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: YTHDC2 Full Name: YTH domain containing 2 Category: mRNA Synonyms: CAHL|hYTHDC2 Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 113513683 End Site(bp): 113595285 Gene Summary: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016] External Links: Ensembl ID: ENSG00000047188 HGNC ID: HGNC:24721 Entrez Gene: 64848

Expression Profile of YTHDC2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES NO hsa-miR-129-2-3p YES NO YES hsa-miR-1297 YES YES NO hsa-miR-1321 YES NO NO hsa-miR-137 YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-155-5p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-7-5p YES YES NO hsa-miR-874-3p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO hsa-miR-96-5p YES YES NO Display: