ctcRbase

Entry Detail

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General Information

Database ID: SKCM07192 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ARFGAP3 Full Name: ADP ribosylation factor GTPase activating protein 3 Category: mRNA Synonyms: ARFGAP1 Chromosome: chr22 Strand: - Coordinate: Start Site(bp): 42796502 End Site(bp): 42858106 Gene Summary: The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008] External Links: Ensembl ID: ENSG00000242247 HGNC ID: HGNC:661 Entrez Gene: 26286

Expression Profile of ARFGAP3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-155-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-422a YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-653-5p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-96-5p YES YES NO Display: