ctcRbase

Entry Detail

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General Information

Database ID: SKCM07299 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ERLIN2 Full Name: ER lipid raft associated 2 Category: mRNA Synonyms: C8orf2|Erlin-2|NET32|SPFH2|SPG18 Chromosome: chr8 Strand: + Coordinate: Start Site(bp): 37736599 End Site(bp): 37759101 Gene Summary: This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012] External Links: Ensembl ID: ENSG00000147475 HGNC ID: HGNC:1356 Entrez Gene: 11160

Expression Profile of ERLIN2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-137 YES YES NO hsa-miR-140-3p YES NO YES hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-195-5p YES NO YES hsa-miR-196a-5p YES NO YES hsa-miR-196b-5p YES NO YES hsa-miR-197-3p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-324-5p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-340-5p YES NO YES hsa-miR-342-3p YES YES NO hsa-miR-424-5p YES NO YES hsa-miR-433-3p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-497-5p YES NO YES hsa-miR-503-5p YES NO YES hsa-miR-543 YES YES YES hsa-miR-7-5p YES YES NO hsa-miR-9-5p YES YES NO Display: