ctcRbase

Entry Detail

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General Information

Database ID: SKCM07311 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TAF2 Full Name: TATA-box binding protein associated factor 2 Category: mRNA Synonyms: CIF150|MRT40|TAF2B|TAFII150 Chromosome: chr8 Strand: - Coordinate: Start Site(bp): 119730775 End Site(bp): 119832863 Gene Summary: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that is stably associated with the TFIID complex. It contributes to interactions at and downstream of the transcription initiation site, interactions that help determine transcription complex response to activators. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000064313 HGNC ID: HGNC:11536 Entrez Gene: 6873

Expression Profile of TAF2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-140-3p YES NO YES hsa-miR-140-5p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-186-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-206 YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-375 YES YES NO hsa-miR-384 YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-599 YES YES NO hsa-miR-613 YES YES NO Display: