Entry Detail



General Information

Database ID:SKCM07315
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:MR1
Full Name:major histocompatibility complex, class I-related
Category:mRNA
Synonyms:HLALS
Chromosome:chr1
Strand:+
Coordinate:
Start Site(bp):181033425End Site(bp):181061938
Gene Summary:MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome. [provided by RefSeq, Jul 2015]
External Links:
Ensembl ID:ENSG00000153029
HGNC ID:HGNC:4975
Entrez Gene:3140



Expression Profile of MR1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-146a-5p
YES
YES
NO
hsa-miR-146b-5p
YES
YES
NO
Display: