Entry Detail



General Information

Database ID:SKCM07358
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:PPCS
Full Name:phosphopantothenoylcysteine synthetase
Category:mRNA
Synonyms:-
Chromosome:chr1
Strand:+
Coordinate:
Start Site(bp):42456117End Site(bp):42473385
Gene Summary:Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCS (EC 6.3.2.5), one of the last enzymes in this pathway, converts phosphopantothenate to phosphopantothenoylcysteine (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM, Mar 2008]
External Links:
Ensembl ID:ENSG00000127125
HGNC ID:HGNC:25686
Entrez Gene:79717



Expression Profile of PPCS Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-132-3p
YES
YES
NO
hsa-miR-137
YES
YES
NO
hsa-miR-181a-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-18a-5p
YES
YES
NO
hsa-miR-18b-5p
YES
YES
NO
hsa-miR-190a-5p
YES
YES
NO
hsa-miR-190b
YES
YES
NO
hsa-miR-212-3p
YES
YES
NO
hsa-miR-24-3p
YES
YES
NO
hsa-miR-25-3p
YES
YES
YES
hsa-miR-324-5p
YES
YES
NO
hsa-miR-32-5p
YES
YES
YES
hsa-miR-329-3p
YES
NO
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-362-3p
YES
NO
NO
hsa-miR-363-3p
YES
YES
YES
hsa-miR-367-3p
YES
YES
YES
hsa-miR-384
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-599
YES
YES
NO
hsa-miR-92a-3p
YES
YES
YES
hsa-miR-92b-3p
YES
YES
YES
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