ctcRbase

Entry Detail

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General Information

Database ID: SKCM07428 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: WWP1 Full Name: WW domain containing E3 ubiquitin protein ligase 1 Category: mRNA Synonyms: AIP5|Tiul1|hSDRP1 Chromosome: chr8 Strand: + Coordinate: Start Site(bp): 86342738 End Site(bp): 86478420 Gene Summary: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000123124 HGNC ID: HGNC:17004 Entrez Gene: 11059

Expression Profile of WWP1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-153-3p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-191-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-21-5p YES YES YES hsa-miR-223-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-335-5p YES YES NO hsa-miR-338-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-448 YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-590-5p YES YES YES hsa-miR-655-3p YES NO YES Display: