| ncRNA Symbol: | KLK2 |
| Full Name: | kallikrein related peptidase 2 |
| Category: | mRNA |
| Synonyms: | KLK2A2|hGK-1|hK2 |
| Chromosome: | chr19 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 50861568 | End Site(bp): | 50880567 |
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| Gene Summary: | This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012] |
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