ctcRbase

Entry Detail

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General Information

Database ID: SKCM07472 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: GUF1 Full Name: GUF1 homolog, GTPase Category: mRNA Synonyms: EF-4|EF4|EIEE40 Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 44678427 End Site(bp): 44700926 Gene Summary: This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] External Links: Ensembl ID: ENSG00000151806 HGNC ID: HGNC:25799 Entrez Gene: 60558

Expression Profile of GUF1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-187-3p YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-375 YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-488-3p YES YES NO Display: