ctcRbase

Entry Detail

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General Information

Database ID: SKCM07474 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: QPRT Full Name: quinolinate phosphoribosyltransferase Category: mRNA Synonyms: HEL-S-90n|QPRTase Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 29679008 End Site(bp): 29698699 Gene Summary: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] External Links: Ensembl ID: ENSG00000103485 HGNC ID: HGNC:9755 Entrez Gene: 23475

Expression Profile of QPRT Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-143-3p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-93-5p YES YES NO Display: