Entry Detail



General Information

Database ID:SKCM07491
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:PLIN2
Full Name:perilipin 2
Category:mRNA
Synonyms:ADFP|ADRP
Chromosome:chr9
Strand:-
Coordinate:
Start Site(bp):19108375End Site(bp):19149290
Gene Summary:The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
External Links:
Ensembl ID:ENSG00000147872
HGNC ID:HGNC:248
Entrez Gene:123



Expression Profile of PLIN2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1297
YES
YES
NO
hsa-miR-146a-5p
YES
YES
NO
hsa-miR-146b-5p
YES
YES
NO
hsa-miR-196a-5p
YES
YES
NO
hsa-miR-196b-5p
YES
YES
NO
hsa-miR-26a-5p
YES
YES
NO
hsa-miR-26b-5p
YES
YES
NO
hsa-miR-296-3p
YES
YES
NO
hsa-miR-302a-3p
YES
YES
NO
hsa-miR-302b-3p
YES
YES
NO
hsa-miR-302c-3p
YES
YES
NO
hsa-miR-302d-3p
YES
YES
NO
hsa-miR-302e
YES
YES
NO
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-372-3p
YES
YES
NO
hsa-miR-373-3p
YES
YES
NO
hsa-miR-520a-3p
YES
YES
NO
hsa-miR-520b
YES
YES
NO
hsa-miR-520c-3p
YES
YES
NO
hsa-miR-520d-3p
YES
YES
NO
hsa-miR-520e
YES
YES
NO
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