ctcRbase

Entry Detail

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General Information

Database ID: SKCM07514 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MCOLN2 Full Name: mucolipin 2 Category: mRNA Synonyms: TRP-ML2|TRPML2 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 84925583 End Site(bp): 84997113 Gene Summary: Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 [PubMed 17662026]).[supplied by OMIM, Sep 2009] External Links: Ensembl ID: ENSG00000153898 HGNC ID: HGNC:13357 Entrez Gene: 255231

Expression Profile of MCOLN2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-32-5p YES YES YES hsa-miR-340-5p YES NO YES hsa-miR-363-3p YES YES YES hsa-miR-365a-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: