ctcRbase

Entry Detail

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General Information

Database ID: SKCM07523 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TTC8 Full Name: tetratricopeptide repeat domain 8 Category: mRNA Synonyms: BBS8|RP51 Chromosome: chr14 Strand: + Coordinate: Start Site(bp): 88824153 End Site(bp): 88881078 Gene Summary: This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. A mutation in this gene has also been implicated in nonsyndromic retinitis pigmentosa. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] External Links: Ensembl ID: ENSG00000165533 HGNC ID: HGNC:20087 Entrez Gene: 123016

Expression Profile of TTC8 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-155-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-197-3p YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-486-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-543 YES YES NO Display: