Entry Detail



General Information

Database ID:SKCM07540
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:EXO1
Full Name:exonuclease 1
Category:mRNA
Synonyms:HEX1|hExoI
Chromosome:chr1
Strand:+
Coordinate:
Start Site(bp):241847967End Site(bp):241895148
Gene Summary:This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000174371
HGNC ID:HGNC:3511
Entrez Gene:9156



Expression Profile of EXO1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-137
YES
YES
YES
hsa-miR-181a-5p
YES
YES
YES
hsa-miR-181b-5p
YES
YES
YES
hsa-miR-181c-5p
YES
YES
YES
hsa-miR-181d-5p
YES
YES
YES
hsa-miR-183-5p
YES
YES
NO
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