Entry Detail



General Information

Database ID:SKCM07546
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:GTSE1
Full Name:G2 and S-phase expressed 1
Category:mRNA
Synonyms:B99
Chromosome:chr22
Strand:+
Coordinate:
Start Site(bp):46296741End Site(bp):46330810
Gene Summary:The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000075218
HGNC ID:HGNC:13698
Entrez Gene:51512



Expression Profile of GTSE1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-134-5p
YES
YES
NO
hsa-miR-181a-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-23a-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-296-3p
YES
YES
NO
hsa-miR-300
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-543
YES
YES
NO
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