ctcRbase

Entry Detail

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General Information

Database ID: SKCM07550 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CMBL Full Name: carboxymethylenebutenolidase homolog Category: mRNA Synonyms: JS-1 Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 10275875 End Site(bp): 10308026 Gene Summary: CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010] External Links: Ensembl ID: ENSG00000164237 HGNC ID: HGNC:25090 Entrez Gene: 134147

Expression Profile of CMBL Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-590-5p YES YES NO Display: