ctcRbase

Entry Detail

---



General Information

Database ID: SKCM07563 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CRTC3 Full Name: CREB regulated transcription coactivator 3 Category: mRNA Synonyms: TORC-3|TORC3 Chromosome: chr15 Strand: + Coordinate: Start Site(bp): 90529925 End Site(bp): 90645345 Gene Summary: This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012] External Links: Ensembl ID: ENSG00000140577 HGNC ID: HGNC:26148 Entrez Gene: 64784

Expression Profile of CRTC3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-1197 YES NO YES hsa-miR-124-3p YES YES YES hsa-miR-1271-5p YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-140-5p YES NO YES hsa-miR-144-3p YES YES NO hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-17-5p YES YES YES hsa-miR-195-5p YES NO YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-300 YES NO YES hsa-miR-340-5p YES NO YES hsa-miR-346 YES YES NO hsa-miR-372-3p YES YES NO hsa-miR-381-3p YES NO YES hsa-miR-424-5p YES NO YES hsa-miR-494-3p YES YES NO hsa-miR-497-5p YES NO YES hsa-miR-506-3p YES YES YES hsa-miR-519d-3p YES YES YES hsa-miR-93-5p YES YES YES hsa-miR-96-5p YES YES NO Display: