ctcRbase

Entry Detail

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General Information

Database ID: SKCM07564 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MTHFR Full Name: methylenetetrahydrofolate reductase Category: mRNA Synonyms: - Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 11785723 End Site(bp): 11806920 Gene Summary: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009] External Links: Ensembl ID: ENSG00000177000 HGNC ID: HGNC:7436 Entrez Gene: 4524

Expression Profile of MTHFR Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-149-5p YES NO NO hsa-miR-214-3p YES NO NO hsa-miR-22-3p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-488-3p YES YES NO Display: